5 DAYS AGO • 4 MIN READ

🌏 Melanoma vaccine cuts recurrence or death risk 42% in phase 3 trial | 🦹 The Tao of genius

profile

Good News for Humankind

A daily dose of inspiration and inquiry.


October 27, 2026

Good News for Humankind 🌏

Your daily spark of possibility — one real milestone for change from around the world.

Melanoma vaccine cuts recurrence or death risk 42% in phase 3 trial

Merck and Moderna’s personalized melanoma vaccine helped keep skin cancer from returning in a phase 3 trial of 1,137 people after surgery. Added to the immunotherapy Keytruda, it cut the risk of recurrence or death by 42%. At two years, 82.2% on the combination were alive without a recurrence, versus 70.0% on Keytruda alone.

Each dose is made from the patient’s own tumor and codes for up to 34 neoantigens, markers unique to that cancer. Fever and injection-site pain were more common, though serious side effects were similar between groups.

It is not approved, and overall survival data are not yet mature. The companies say they are talking with regulators.


Antihero Project 🦹

You've read the good news. Now, start making your own.

​

Chapter 5: Passion | 5-2 The Tao of genius

Genius is the capacity within all humans to bring something entirely new and unexpected into being.

In this sense, though it’s perfectly human and natural, it also feels almost like magic or divine intervention. One moment our minds are blank. In the next, an entirely new idea or possibility has arisen, seemingly out of nowhere, often through no perceived doing or intention of our own.

How this creative spark comes to us or what circumstances provoke it remains largely a mystery. We may try to create definitions, frameworks, or philosophy to pin it down. And we might try to capture the essence of our own unique flavor of genius. But this is ultimately a fool’s errand, an attempt to give shape to liquid or words to the ineffable.

This is similar to the notion expressed in the first lines of the Tao Te Ching:

The Tao that can be told
is not the eternal Tao
The name that can be named
is not the eternal Name.

The genius that can be fully explained, expressed, or captured is not our true genius. Our deepest, fullest genius remains always just a bit beyond our mind’s conscious grasp. There will always be ways to know it more deeply. There will always be more left to discover.

But it still may be helpful to describe it, however imperfectly. So let’s try.

Think of your genius as a stew, not a salad. Its ingredients don't sit neatly beside one another. They cook and blend into one another. Over time, new flavors and textures arise. Together, they become something none of them is alone, something that can never be reduced back down to its parts.

This is a recipe only the universe knows in full. But we can at least start with three key ingredients: passions, talents, and values.


This is an excerpt from my upcoming book The Antihero's Journey: From Burnout to Real Contribution in Polycrisis Times. To read other excerpts, go here.

Peter Schulte

Burnout & purpose coach, recovering hustle hero.

​

Go deeper 🦋

Antihero Practice & Accountability

Commit to and get support in removing drains and distractions from your life, so you can focus your energy on what matters most.

Let's chat

Book a 1:1 call with me to explore how I might support important life and career transitions, or just to say hi and get to know each other. I love getting to know my readers either way.

No charge. No strings.

The Course

The Antihero's Journey is a self-paced introduction to my core philosophy and practice. Written teachings, videos, and exercises on burnout, purpose, and social impact.

$45 for a limited time.

The Program

Antihero Project is my small-group program for people who care deeply but are ready to make their contribution in a new way — without the burnout and self-doubt.

Includes the course and online circle.

​

​Unsubscribe | Preferences | Switch to weekly digest

Peter Schulte Coaching LLC
​
1229 Cornwall Ave. Suite 204, Bellingham, WA 98225

Good News for Humankind

A daily dose of inspiration and inquiry.